At least from my history, the only party I've seen experience a
TPK was the one that entirely focused on dealing damage as opposed to having powers with buffs of conditions.
4E has tons of synergy potential if people choose to explore it.
IE) If your controller focuses on conditions like slow/immobile, your party can put a decent focus on ranged attacks to spike enemies in those encounters. This was extremely effective to a degree where it got silly in my campaign. Mainly because too many creatures in heroic tier MM1 do NOT have a ranged attack option. I found myself having to give them slings/crossbows on the fly in order to put some fear in the battle.
Or...combine nasty zone effects/sustained AOE with melee characters who can push/slide in order to maximize the effects.