magical happenings in Sanctuary -
Ischade is a well-known witch and vampire
Targ (Cade's companion) is werewolf (or something very close)
Khamwas the wizard has an improved familiar called a manikin, named Tjainufi
Noteable, the cat, used to be a man
again, these are just a few of the things i've jotted down about the more unusual things in Sanctuary (this, of course, doesn't include the plethora of wizards and several demi-gods living in the city....)