Edit: Sorry, a bit of a ramble. I'll try to clean this up tonight.
Um... this sounds ... weird. I'm trying to find a way to understand this without people thinking I'm saying "scientists are stupid." This seems to say that if our calculations don't match observation, then we decide our observations are wrong or incomplete. Isn't this the definition of "bad science"? Shouldn't "good science" refigure the math to match observations rather than hold firm to incorrect math (incorrect according to observation)? I fully posit that it's obvious I'm just not getting this idea.
Isn't this how aether theory was believed for a while.
Bullgrit
In detailed literature, there are collations of explanations for phenomena (what we observe), with an exporation of different explanations, and the necessary adjustments to current known laws for a particular explanation to work. Those necessary adjustments can lead to predictable results in associated phenomena, which can pretty much wreck a candidate explanation.
I found this sort of collation googling explanations for the red shift a while back. All sorts of explanations have been explored, and discarded due to solid evidence, leaving, more or less, universal expansion as the current best explanation.
I would think that that exhaustive searches are ongoing for explanations, with folks looking in all sorts of directions. For example, one might try to explain unexpected measurements of radial velocities of observable matter in galaxies by postulating a modification to the inverse square law of gravity. That would have a measurable consequence in other areas, which will be looked at, and the scientific community would, over time, make a judgement of whether the explanation was compelling.
At this level of detail, there would end up being an enumeration of explanations, with qualifications attached to each as the quality of each explanation, with a sense of "this is it" applying to one or another explanation only after enough evidence was gathered.
I would guess that all of the following, and more, are or have been considered:
Measurement errors (somehow, we aren't measuring the phenomenon accurate);
Analysis errors (we measured it correctly, but aren't reasoning through the data correctly)
Errors in currently accepted physical theories (some equation which is being used has a necessary modification which we aren't making)
Errors in our understanding of the underlying physical reality (our basic idea of what is there to explain is missing an important detail)
I'm thinking that a modification to a widely held law (say, the inverse square law of gravity) would be looked at pretty hard, since an observably provable modification would be a very big deal, but somewhat on the fringe, since fundamental changes are pretty rare things.
These provides a little information:
https://en.wikipedia.org/wiki/Galaxy_rotation_curve
Though dark matter is by far the most accepted explanation for the resolution to the galaxy rotation problem, other proposals have been offered with varying degrees of success. Of the possible alternatives, the most notable is Modified Newtonian Dynamics (MOND), which involves modifying the laws of gravity.
And:
Alternatives to dark matter
There have been a number of attempts to solve the problem of galaxy rotation curves by modifying gravity without invoking dark matter. One of the most discussed is Modified Newtonian Dynamics (MOND), originally proposed by Mordehai Milgrom in 1983, which modifies the Newtonian force law at low accelerations to enhance the effective gravitational attraction. MOND has had a considerable amount of success in predicting the rotation curves of low-surface-brightness galaxies, the baryonic Tully–Fisher relation,and the velocity dispersions of the small satellite galaxies of the Local Group. These results are surprising in the context of dark matter, which does not predict the same things as MOND without considerable fine-tuning.
I would be very very careful before accepting the above quotes as being mainstream within the the scientific community. This is, I'm thinking, one of several areas where non-scientific literature does a poor job of representing the general scientific viewpoint, at least so far as presenting the current prevailing thoughts. A particular exciting alternate theory can garner a lot more attention than it deserves, and because of the extra attention, seem to have a lot more support than it really does.
Thx!
TomB