For me its The Good Friends of Jackson Elias (unable to post links as I'm a new member but if you search for that name or Blasphemous Tomes I assume you'll find it ok!). They're billed as a horror podcast, discussing horror with relation to gaming, and theres very good chemistry between the three presenters. They recently interviewed James Raggi of Lamentations of the Flame Princess fame, was a blinder of an episode.