I'm actually running this game already, using my home-brew "Unspeakable Futures" game that I originally built back in the early 3.0 days (and then later influenced by d20 Call of Cthulhu, d20 Modern, and then 3.5), but updated to work with the Pathfinder rules. The game's sort of a Lovecraft meets Mad Max meets Fallout meets the Dark Tower type mashup.
Whether or not it'd make a good game for us to publish at Paizo... we'll see, I guess! It's certainly fun to play! (Last session saw the PCs fighting ghouls, a mad robot, and a giant albino sewer crocodile while exploring a partially collapsed subway system. And a near TPK to boot!)