What sort of saves do you foresee being tied to abilities like Strength and Intelligence, or are you going to follow the 4e model for allowing different attributes to affect a single save? If you aren't going this route, I'd be curious to hear what steps is the Odyssey system taking to balance the value of all the different saves, or how do you determine what save is appropriate for an ability to target?
"Saves" are perhaps the wrong word, since they're all "Checks" now -- against opposed rolls, etc.
You could roll a WIS check to resist the effects of mind-control; a DEX check could be used against an area attack; an INT check could be used in opposition to being given false information, etc.