Nobody knew who Iron Man was prior to the RDJ film, except that it was something on some cartoon they saw or their kid watched or something? D&D and tabletop games in general easily have as much cultural penetration as 2nd tier Marvel characters like Blade and Iron Man.
Hollywood is going to look for things with story potential and geek cache. D&D is having a moment, and therefore raising the profile of tabletop in general. I don't think it is a stretch at all tobelieve that if the D&D movie is good and Cavill's 40K works, Hollywood is going to dip into the ttrpg field for the Next Big Thing.