Most of the arguments against hexes can be reduced to "drawing on a hex grid is (supposedly) harder".
A few weeks ago, while we were discussing the matter of the 'irrealistic' 4E diagonals on it.hobby.giochi.gdr.dnd, Vincenzo Beretta suggested this brilliant solution: a hex-like distribution for squares (or, how to square the hex).
I've made a pdf sheet for use with my tokens you can find
here.
I used this for my (fast-play) 4E demos at my gaming club's convention last weekend, and I must say it really is a reasonable compromise - almost as good to spot movement at a glance as real hexes, but with a lot less wasted space in dungeons and the like.