Why would anyone make a D&D game anyway now?
Because many fans of the game would thoroughly enjoy a 4E CRPG.
4E doesn't have any fluff at all and the setting many people are used to were completely destroyed. It doesn't offer any advantages besides the D&D name.
Except for the fantastic fluff of the core setting, which could easily set the stage for a CRPG set in the Nentir Vale. As well as having rewarding settings to use like Eberron - almost universally agreed to be a big success for 4E - and Forgotten Realms - which, however much some might complain about it, has proven a solid launching point for the incredibly successful Living Forgotten Realms.
And as disadvantages you have Hasbro/WotC meddleing with the development. Not to mention that the 4E combat system is hard to do in a real time way.
I think you'll need to expand on 'WotC meddling with development' before it becomes a real complaint. As for the difficulty of the system, there were also many who felt the same about 3rd - yet it was doable. I'm relatively confident that there are a variety of ways to smoothly map the 4E system onto a video game.
So, why go through all this trouble when you instead can make your own setting or just license some russian fantasy book (which costs much less)?
Because of the incredible success of NWN and other previous CRPGs?