I'll be interested to see where it goes, but I am not terribly worried by paladins no longer being immune to disease, it was a story beat for "purity" purposes that just didn't make a lot of sense when so many other classes should have something similar, but don't.
I would like to note that easy access to Remove Disease (whether in the form of Lesser Restoration, Laying Hands, etc) has some use beyond just being a story beat. It's helpful as an in-game hand wave for why player characters never come down with a cold or strep throat while adventuring. It's something that is generally assumed to happen off screen (like maintaining equipment by cleaning your sword or treating your leather armor), but adds to verisimilitude.
It's also an often forgotten background in world building. I real life sword-and-armor times, even minor bacterial infections could be quite deadly. They're not a big concern in D&D. Magical medicine is the reason, even if it's not a conscious decision by the world's creator.