The adventure works well for 4-5 players, not sure if anything changes much otherwise.
Compared to 4e the level 1 PCs are squishier, and I had half the party incapacitated in the Cragmaw Hideout. For the exploration of locations it can be good to draw them as the players explore (see of you can find the D&D team playing the adventure for an example). However, I have mostly not found it useful to keep track of all positions precisely enough to use a grid. The first encounter was over way too fast. Having something to show the scene can be good. Maybe use tokens or minis to show who are close together and the approximate position relative to others.
Compared to 4e the level 1 PCs are squishier, and I had half the party incapacitated in the Cragmaw Hideout. For the exploration of locations it can be good to draw them as the players explore (see of you can find the D&D team playing the adventure for an example). However, I have mostly not found it useful to keep track of all positions precisely enough to use a grid. The first encounter was over way too fast. Having something to show the scene can be good. Maybe use tokens or minis to show who are close together and the approximate position relative to others.