Though a wall of force can be disintegrated. But that's not my objection. What bothers me is that Wall of Force is a Concentration spell. So is levitate, detect thoughts, and dominate monsters. But dominate monster is once a day, so cast that and then wall of force. Seems like the EB could do it on the same round. Dominate monster as an action and wall of force as initiative count 20 lair action.
Yeah, I think I'm talking myself into this. Wall of Force makes a lot more sense. The elder brain can sink into the brine pool and cast wall of force scooping so it is surrounded by brine in the wall of force.
The one issue with this is how does it levitate from the resting pool to the elder-brain chamber (as shown in the example map). Casting levitation requires concentration. I guess a mind flayer could levitate it. I also suppose that there could be a smaller brine pool in the Elder Brain Chamber and some kind of valve-like portal that allows the elder brain to move between the resting pool and the elder brain chamber without emptying the smaller brine pool in the elder brain chamber.
Really, my issue is turning out to be more about the map on VGM page 79. The Elder Brain Chamber makes no sense if it is just using a wall of force. Actually, I see little utility for that room at all. And everything else I've ever read about Illithiad only discuss the elder brain residing in a brine pool. It makes more sense that it would just have the "resting pool" and would throw up wall of force when a threat presented itself.
A separate Elder Brain Chamber only makes sense if the EB holds court with non-illithiads, which doesn't seem very much like mind flayers. But if it did, I could see it wanting to take visitors in a room removed from where the tadpole chambers are.
Hmmm... so I think I'm back to using Wall of Force as the explanation. That's actually tougher to defeat. Really, only the disintegration spell with counter it. Or you have to find a way to break its concentration.