Yes, that might work. Do you think it wouldn't?
How would you implement dailies or milestones? If you did not bother with these or found a different mechanic (in encounter combat morale for example) it could be feasible. But all the maps and groups of maps should be tied for a campaign driven reason to visit and explore and track-. Also there in ja there was a big excitement about the goodies you found in the maps while exploring or eliminating the enemies: they did not just influence your abilities, they created them: grenades, firearms, bullets, explosives, heavy weapons, armor etch. How would you deal with 4e regarding these two things?