I'd allow you to have line of sight only IF you have the mirror oriented just right. You still wouldn't have line of effect if there was something in the way, as normal, since you can't just bounce spells off a mirror. It seems too situational to be of any real use, though, and only if the DM says you're at just the correct angle to see the target.
Imagine a U-turn dungeon corridor with a giant mirror for back wall. You get close enough to see an Ogre, but there's still a wall in between you two. Unless you have something like a Burrowing psionic power (to get through the wall) or a spell that ignores line of effect (I think a good example is call lightning, which comes down from the sky and only works if there's no roof) there's not a lot that you can do.
Although, it's arguable if a mirror would allow you to accurately target creatures. I mean, it seems like something a movie trickster would try to do. I'd make it a Skill Trick: Reflection Targeting (requires, say, Spot 5 ranks). "You have line of sight to a creature if you have line of sight to it's reflection. If it's reflection has cover (say, you only have a small mirror and can only see part of the creature) the target creature has the same cover. If the reflection is of poor quality (that is, moving water, a thin sheet of ice, etc... anything less than a clean mirror) then the target creature has cover."
That way, you could only really use it once per encounter without specializing.