Trip is a combat tactic, like Feint, that allows you to get your opponent Prone. I realize that Prone isn't Helpless, a Helpless delender not only gets a +4 to hit against him, but he also gets an automatic Critical Hit.
I think the phrasing "anytime the defender is unable to effectively defend himself" is the key here. I would think that anything that gives you a penalty to your AC is not allowing you to fully defend yourself. If you Feint someone in combat, you deny them their Dex bonus to AC, whether they have a dex bonus or not. So their AC may or may not change. When you Flank someone, you get a +2 against them, which is basically the same thing as him gettin a -2 to AC because he cannot "effectively defend himself" from your attack. When someone is Prone, they get a -4 to AC, so this definitely affects the actual AC, which to me translates to "unable to effectively defend himself."
My point is that a specific penalty to AC is a more favorable circumstance for the attacker than a denial of a Dex bonus because a minus to AC is a minus to any defender's AC, while a denial of Dex bonus will only affect the AC of defenders that actually have a dex bonus to AC...
I think the phrasing "anytime the defender is unable to effectively defend himself" is the key here. I would think that anything that gives you a penalty to your AC is not allowing you to fully defend yourself. If you Feint someone in combat, you deny them their Dex bonus to AC, whether they have a dex bonus or not. So their AC may or may not change. When you Flank someone, you get a +2 against them, which is basically the same thing as him gettin a -2 to AC because he cannot "effectively defend himself" from your attack. When someone is Prone, they get a -4 to AC, so this definitely affects the actual AC, which to me translates to "unable to effectively defend himself."
My point is that a specific penalty to AC is a more favorable circumstance for the attacker than a denial of a Dex bonus because a minus to AC is a minus to any defender's AC, while a denial of Dex bonus will only affect the AC of defenders that actually have a dex bonus to AC...