Also check out AEG's Swashbuckling Adventures, which, as I recall, is the D20 version of their 7th Sea game...which you should also check out.
Dannyalcatraz said:GURPS, while I hate it, would probably model it just as well. An excellent choice if you like the system. Bonus: it probably has the most number of quality supplements that would help you with the campaign- ask Jürgen Hubert or Pawsplay for details.