At which point you're at odds with "smart play."
Sure, I guess.
Talk about Shroedinger.... A lycanthrope is both vulnerable to silver and immune to silver.
I guess the DM could make the determination based ona die roll weighted in favor of the MM option being the one that is actually true so that the original "smart" option stays true to being the smartest choice.
That's one option.
Cool. So once you realize that despite being at full HPs your narrative wounds still hurt you, things should remain that way, and now resting to heal your narrative wounds should be the smart option...
...you're barking up the wrong tree, here.