Traveller! The default setting makes a few questionable assumptions about how FTL travel works, but at least in Mongoose Traveller, there's a full page of "rules for ignoring the rules of jump drive," including things like more standard hyperspace, jump gates, &c. The default setting is kinda hard-science, but those assumptions can be easily hand-waved away ("How long does it take to get far enough away from the planet to jump?... Does anyone really care? No? OK, it happens, we're good.").
In short: definitely check out Mongoose Traveller. I ran a game of it last semester and it was one of the more fun things I've played in a long time.