i don't know anything about Gibson (except he writes "Neuromancer and Post-Modern Science Fiction"..)
are you planning on adding psionics? (like Akira?)
Ghost in the Shell - "The ultimate secret agent of the future is not human, has no physical body and can freely travel the information highways of the world, hacking and manipulating whatever and whenever required.
The agent, created by the Ministry of Foreign Affairs, is designated code name Project 2501 and distanced from them under the pseudonym "The Puppet Master." 2501 seems to be the perfect solution to their international espionage requirements. Everything runs smoothly until this prototype virtual agent concludes it is a life form in its own right "born in a sea of information" and requests political asylum and true physical existence in defiance of its creator."
Appleseed - "After the devastation of World War 3, the scattered governments of the world construct the perfect city administered by perfect Bioroids - artificially created half human/half robots. Life in Olympus is carefully controlled and monitored, however some of its human population have had enough. A dedicated band of terrorists plot to destroy the central computer and restore freedom to mankind. Will they be stopped before they ruin the dream of paradise?"
Akira - "Tokyo, as we know it, was destroyed by a kind of a new super-bomb of unknown origin. 9 hours after, World War III broke out and most of the major cities in the world were completely destroyed. 31 years after, Neo-Tokyo now stands, were the old Tokyo has been. One night, Kaneda and his motorcycle gang have an accident with a little boy with a wrinkled face, as one of an old man. Tetsuo, one of the gang's members crashes into the boy, who mysteriously remains unhurt and then simply vanishes from the eye. Tetsuo is brought to Hospital, and everything seems to have normalized. But that is not at all the case:
The strange boy from the last night was a part of a secret military project dealing with supernatural powers. The project is lead by the "Colonel", who wants to develop human weapons with aid of these powers. On his trail are Ryu and Kei (not Kay), members of a semi-terroristic group, who want to discover and destroy his plans. And now Tetsuo is going to be a new member of the project. But his powers rise much faster than the Colonel has expected. Tetsuo manages to find out the location of an underground freeze chamber, where the mysterium AKIRA is kept. Akira, too was a member of the project. But why did they put him in the freeze chamber at 0,0005 Kelvin ? They were afraid of something. Something they couldn't control anymore. Something Tetsuo is going to set free really soon. . .
And in midst of all the trouble: Kaneda and Kei. "
totally cheating, i know, but those are some synposes from the 'net
so, what have we got? 1) the government (or some agency) is the bad guy (that's easy)
2) the world is 'getting away from' your average human being (being populated by androids, taken over/destroyed by super-powerful telepaths...)
3) terrorists play a role, for or against
so, what side are the PCs on? (good-guy terrorists (free the telepaths!), bad-guy terrorists (if we can't have it, no one will!), good-guy government (we protect the populus!) or the bad-guy government (we'll kill you for what you've discovered!)?