For those lurkers who have never played Talisman, it works like this.
Everbody picks a character from those provided. Each character is sort of a race/class combo all in one. Elven archer, Swashbuckler, Necromancer, Vampire, Thief, Dwarf Warrior, Holy Warrior, etc.
Each character has Strength and Craft. Two simple attributes. Each character also has four lives. Lives are basically like HP. You also start with a gold piece each. The characters all have an alignment, good, neutral, or evil. And they can gain experience points from performing quests or killing monsters. XP can then be traded in for a bonus Craft, or Strength, or Gold, or Life. Each character also has some sort of special ability or two or three. For example, the Vampire could animate monsters he has killed and have them fight for him. The Prophetess could see the upcoming adventure cards. The Wizard got bonus spells, etc.
The board has different zones and regions that you go through. You roll dice and move your character in one direction or the other around the board, passing through different regions, and following the instructions of the space you land on.
Some of the spaces have special rules. Like if you go to the Graveyard, the evil characters can receive some special perks, they roll a die and can gain a gold, a life, or bonus Craft or Strength. Good characters might lose a life, or have something else bad happen.
But most spaces require you to draw one or more Adventure cards. These cards could be treasure, monsters, events, or NPC encounters. Monsters you have to fight and if you beat them you gain XP and any treasure cards they might be guarding. Events affect everyone in a certain region, or on the entire board. For example, you might get Blizzard and everyone in your region can now only move one space for the next two rounds. You can also meet NPCs. Witches who might hex you, Merchants who might sell you stuff that you can buy with your gold, or even someone who agrees to become your follower. They travel with you and provide some special benefit to your character. Like they can help you fight, or carry some of your treasure since you are limited in the amount of treasure you can carry.
Some treasure, is just valuable stuff that you can sell, other treasure includes weapons, armor, magic items, etc.
If you land on another player's spot, you can trade with them, or try to fight them and if you win, they either lose a life or give you some of their stuff.
The ultimate goal of the game is to become super powerful and then enter the Dragon's Tower. The Dragon's Tower is the most difficult region in the game. Full of uber traps and tough monsters. You can't even enter the tower unless you have a talisman (hence the name of the game). You can get Talismans by going on quests from some of the NPCs you meet, or by finding one, or trading for one, or killing for one. At the top of the Dragon's Tower you fight the dragon. If you win, you win the game. If you lose, bad things happen to your character.
Depending on the number of players the game takes about 3-6 hours to play through.
Anyway, there is much more to it than that, for example, I didn't even mention that some characters can use spells, or that some monsters fight you with Craft instead of Strength, etc. but that should sum it up for those who have never played and are interested.
Its an awesome game. I love it.