Glad someone mentioned Spire, I was going to as well but for a different reason. I can't remember where I first encountered this analogy, but I think it's a good principle of worldbuilding for this medium: set up your world so that it's a powder keg about to blow.
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Spire is a great example of this. The setting is incredibly detailed (some might say too detailed), but everything's constructed with player engagement in mind; the city's absolutely packed with fuses to light. Even if the action of the campaign is confined to just a single district, you've got extremely good odds that after a few sessions, much of the setting, if not all of it, will never be the same again.