When I was a kid we played at people's homes, in the cafeteria at school, or in public libraries.
Today, I exclusivley play in my, or someone else's, home. I don't think I would enjoy gaming in either of my two local FLGSs. One is usually filled with Warhammer players who *really* look down on D&D, and enjoy telling you that your favorite game sucks, and I just don't want to deal with it. The other is filled with pre and early teens bickering about Neopets and click-based games, or drooling and making rude comments about the BoEF. As a certified Grumpy Old Fart (TM), I'm not really interested in that either.
Having said that, I have volunteered to run a few D&D games at one of the stores in an attempt to introduce it to new players, in conjunction with the 30th anniversary of D&D. I am looking forward to that.
Edit: Just wanted to make it clear that I don't begrudge the guys in the FLGSs their game or their place to run it.