Divine Soul is a subclass that I find really interesting and want to try out, but it's tough to come up with many new metamagic synergies from the cleric list. There are a number of touch spells that can become ranged using distant spell (Inflict/Cure Wounds, Bestow Curse, Contagion), and situational spells that could benefit from Twinning (Restorations, Revivify, etc.), ... I guess making Aid or Death Ward last 16 hours has some value, since you can use leftover slots the night before and still get 8 hrs out of them the next day, but doesn't seem worth a metamagic pick. And Subtle is always fun: Animate Dead, Geas... But most of these are pretty situational. Quicken Spirit Guardians followed by Twinned Lightning Lure, to bunch up as many creatures as possible so you can get within 15' ft of them? What synergies have you come up with?