I changed the disabled, dying, and dead thresholds to be, respectively, 0 to -(Con mod), < -(Con mod) to > Constitution, Constitution. So someone with a Con of 17 is disabled at 0 to -3, dying from -4 to -16, and dead at -17. I stole this from Arcana Unearthed.
No, it's not a minor change, but seeing as I have only four house rules, it is the least significant change.
I highly recommend this rule, BTW. It requires, at most, one extra entry in a stat block, and it goes a long way toward PC survival. It's worked out very well for us.