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Message: <blockquote data-quote="Mr. Teapot" data-source="post: 4198725" data-attributes="member: 62191">The angels we saw had abilities where they had higher defenses as long as they were unhurt (IIRC).  If you had an enemy that dropped in defense once bloodied you might want to save the big guns until you were more certain that they would hit.  Lots of Dailies seem to involve Miss effects, but encounter powers don't have that as much.  So you wouldn't want to waste them if you could improve your chance of hitting later in the battle.(Similarly, if you think you could get a better chance of hitting later on, through flanking or an ability that gives you a bonus when you are bloodied or other things like that.)</blockquote>