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Message: <blockquote data-quote="shilsen" data-source="post: 1408744" data-attributes="member: 198">See Table 8-6 on pg. 151 of the PHB for some of the answers.When attacking into a grapple with a melee weapon, there is no extra chance of a miss. With a ranged weapon, you roll randomly to see which target you hit. So size of the grapplers would not be relevant when attacking with a melee weapon, but would be if using a ranged one.The same would be true for a melee touch attack (no miss chance) or a ranged touch attack (roll randomly).I'm not sure what you mean by a spell effect that touches only a larger grappling creature. A targeted spell would affect a target as normal, grappling or not. A spell requiring a touch attack would be affected as above. If you mean an area effect, that would require DM adjudication since the rules don't spell it out either way.</blockquote>