I was pretty impressed with Blankets by Craig Thompson. Very personal and very touching. Huge book (especially for a comic) but I read it all in one sitting.
I thought that Terry Pratchett's Wee Free Men was a real hoot.
As far as fantasy stuff goes, my favorites have been the Kane books by Karl Edward Wagner. There are three of them: Bloodstone, Dark Crusade, and Darkness Weaves. Very cool stuff. The character Kane is like a cross between Robert E. Howard's Conan and Conan's arch-nemesis Thoth-Amon.