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Message: <blockquote data-quote="reanjr" data-source="post: 3104003" data-attributes="member: 20740">We did something like this.  All effects were noncumulative for the same target area and status type effects last 1d4 rounds unless otherwise noted:Eye: For DC 10+dmg or blindedHead: For DC dmg or unconsciousTorso: For DC 5+dmg or sickenedHand: For DC 15+dmg or -2 to attacks/skill checks with that handArm: For DC 10+dmg or -2 to attacks/skill checks with that handNeck: For DC dmg or 1d4 Con dmgLeg: For DC dmg or 1/2 movementFoot: For DC 10+dmg or -2 to skill checks related to movingIn addition, on a crit, the effect was permanent (or dead in the case of the head or multiplied by the crit multiplier in the case of the neck).  Regen or something similar would fix these problems.I may have the exact DCs off, but I think those were it.  Basically, for balance (more than realism) the DC was based on how debilitating the effect was.Also forgot to mention that called shots were full-round action.EDIT: (after reading Diaglo's staking post)I kind of forgot about this one.  Heart shot could be performed as I previously specified (as a Diminutive +4 AC creature) with the added effect that it was always considered to have cover from the sternum and also had total concealment (50% miss chance).  So an average unarmored human heart shot would be AC 18 with a 50% miss chance.  Successful hits brought about immediate staggering (0 hp).</blockquote>