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D&D and the rising pandemic
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<blockquote data-quote="Umbran" data-source="post: 8139534" data-attributes="member: 177"><p>So, because biology is incredibly complicated, we need to talk about the difference between infection, and disease. In many North American bat populations, infection with the virus that causes rabies is endemic - pretty much every bat you come across is likely to be infected. However, bats <em>show no symptoms</em> of rabies. </p><p></p><p>If we want to be picky (and here, it pays to be so), the disease is not the infection, but a collection of symptoms - often called a "syndrome" - caused by that infection. The virus we are dealing with is SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), and the disease is covid-19 (Coronavirus Disease - 2019). So, technically speaking, we can talk about immunity to infection, and immunity to the disease separately.</p><p></p><p>The basic test for efficacy of a vaccine is a test for whether you get the disease. The vaccine typically manages this by reducing the viral load down to levels such that it cannot cause disease. This usually means that your viral load is also low enough that you cannot effectively transmit the virus. The fact of the matter is that it is terribly uncommon for a vaccine to make you immune to the disease, but also infectious. </p><p></p><p>However, when a scientist says something is "not entirely clear" that usually means they haven't <em>SPECIFICALLY</em> tested that scenario, which would require an entirely different testing regimen. So, the scientist, being totally truthful, can't tell you for absolute certainty that you aren't shedding virus, because they've been busy testing whether it will make you sick. The fact that they haven't tested that specific issue does not mean there's any real concern around it in terms of the health benefits of the vaccine.</p></blockquote><p></p>
[QUOTE="Umbran, post: 8139534, member: 177"] So, because biology is incredibly complicated, we need to talk about the difference between infection, and disease. In many North American bat populations, infection with the virus that causes rabies is endemic - pretty much every bat you come across is likely to be infected. However, bats [I]show no symptoms[/I] of rabies. If we want to be picky (and here, it pays to be so), the disease is not the infection, but a collection of symptoms - often called a "syndrome" - caused by that infection. The virus we are dealing with is SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), and the disease is covid-19 (Coronavirus Disease - 2019). So, technically speaking, we can talk about immunity to infection, and immunity to the disease separately. The basic test for efficacy of a vaccine is a test for whether you get the disease. The vaccine typically manages this by reducing the viral load down to levels such that it cannot cause disease. This usually means that your viral load is also low enough that you cannot effectively transmit the virus. The fact of the matter is that it is terribly uncommon for a vaccine to make you immune to the disease, but also infectious. However, when a scientist says something is "not entirely clear" that usually means they haven't [I]SPECIFICALLY[/I] tested that scenario, which would require an entirely different testing regimen. So, the scientist, being totally truthful, can't tell you for absolute certainty that you aren't shedding virus, because they've been busy testing whether it will make you sick. The fact that they haven't tested that specific issue does not mean there's any real concern around it in terms of the health benefits of the vaccine. [/QUOTE]
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