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Message: <blockquote data-quote="Shemeska" data-source="post: 2197953" data-attributes="member: 11697">1) It's nothing new.2) I'm a type one diabetic myself, and have had the disease for 13 years. I'm growing rapidly jaded by the research approaches that are getting the most funding, and I'm tired of false hope that's wrapped up in the guise of anything but. Still, that said, I don't expect to be a diabetic 15 years from now.And yes, TNFa is pretty damn nonspecific, but the same researchers have done some interesting work that seems to suggest that it's possible to reset a level of immune tolerance to transplanted islets derived from donor spleenocytes. However it has only happened in mice so far, though the earlier experiments in mice have worked with xenotransplanted human tissue as well. I'm keen on it to say the very least. The white cell experiments also have me very curious, both as a diabetic and as a cell biologist just to see what's actually going on. However I'd hate to cure the diabetes and end up with leukemia a few years later, so mucho safety testing needed even in the best case scenario of the cells producing insulin and sticking around in the human bloodstream.And as for the diabetics with AIDS. Nothing has been published looking at it, but it's an interesting question. But it's a case of saving the city from a mongol horde by burning it to the ground. I'd rather have the diabetes than the HIV <img src="https://cdn.jsdelivr.net/joypixels/assets/8.0/png/unicode/64/1f609.png" class="smilie smilie--emoji" loading="lazy" width="64" height="64" alt=";)" title="Wink    ;)"  data-smilie="2"data-shortname=";)" /> But I'm not sure off the top of my head how large a subset of the T cells are involved in the autoimmune response against the islets, and following that, how much towards full blown AIDS you'd need to be before you ended up with the diabetes possibly reversing. Can't say for sure.</blockquote>

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