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Message: <blockquote data-quote="Nevvur" data-source="post: 7325922" data-attributes="member: 6783882">Most fantasy settings assume an earth-like setting except where explicitly mentioned, and Earth has a huge variety of genetic diseases. It stands to reason, then, that most fantasy settings have these conditions, too, even if they don't come up in the narrative often. Aside from the choice of word 'disease,' and in some cases specific symptoms, there's not a lot in common between inherited and communicable diseases. To point, I think they're generally classified as "genetic disorders" rather than "genetic diseases" these days, though some still wear the word (e.g. Tay-Sachs disease). For spells and feature which cure disease or provide immunity to it, I feel the RAI is to only affect communicable disease. Still, an argument could be made to include inherited disorders.1) What's your take? Personally, I'm comfortable omitting them from the types of conditions those spells/features affect, but I also see the potential for interesting story elements the other way. For example, a character that comes from a long family line of paladins whose forebear started the tradition in part to combat his sickle cell anemia.2) Assuming you don't allow disease immunity/lesser restoration to remove genetic disorders, is there any magic that can (short of Wish, which I assume most DMs would approve). How about Heal? It's a 6th level spell, techincally more powerful than bringing a person back to life! Surely it can fix a few errant chromosomes? Could the beneficiary of such an effect change in appearance if their disorder caused obvious physical abnormalities (Down's Syndrome)?</blockquote>

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