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Message: <blockquote data-quote="Jeremy E Grenemyer" data-source="post: 1921196" data-attributes="member: 12388">My quick and dirty advice:  A DM needs to start by lining up enough adventures to more or less cover levels 1-25, and then organize those adventures around a common theme or metaplot that links them together.  The DM can then break down the adventures into groups consisting of three or four major interrelated plot lines that the PC's will uncover and interact with as play progresses.The DM should plan for the PCs to defeat a BBEG linked to one of the plot lines on or about level 20, and should also work to lay the groundwork for the other story lines by establishing the presence other BBEGs and organizations at various points along the campaign.The DM should save his metaplot for when the PCs turn Epic, and also use this opportunity to give the PCs a glimpse at the full tapestry of interrelated mysteries that have been unfolding over the course of the campaign.Finally, Dragon magazine has been a huge boon for my campaign because it provided me with three superb Epic Level Adventures to point my campaign to from early on.  These adventures have got me covered adventure-wise from levels 21-25.  Even better: These Epic adventures also indirectly provided some good seed ideas on how to tie in lower level adventures into a single campaign metaplot.</blockquote>