I plan on using them. The "Advanced Players Guide" from SSS (Sword & Sorcery Studios) has a section for interesting effects of low and high stats. As written, the make low stats better (with Heroic Merits) and high stats bad (with Tragic Flaws). I wouldn't use 'em as wirtten, but I intend to use the Tragic Flaws (some of which I'll mention below) as UA-Style flaws (with a prereq of related stat 19+). There are 6 per stat, here's a few of my fav's:
Str 19+
Killing Hands (can't choose to do non-lethal damage, ever)
Ravenous Appetite (must eat 3x food per day to sustain self)
Dex 19+
Daredevil (in any life-or-death situation, including standard combat, cliff walking, etc., make will save or do the most daring, spectacular & dangerous thing possible)
"Why, of course I can climb with one hand while fighting off the giants that are chasing us...you guys go ahead!"