Bourne Supremacy - the car chase at the end - that rocked - one of the best of all time, I think. Though all of the chases in that movie (and its prequel) were really well done - smart.
And I'm someone who HATES stupid, pointless chase scenes. I like it when they are part of the core plot - I hate it when they are just an excuse to show some running and some inept chasing.
Oh, and the French Connection chase is a CLASSIC - Gene Hackman trails the L-train in his car - talk about sweet... heck, I had to study that one in film school.