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Message: <blockquote data-quote="apoptosis" data-source="post: 3674049" data-attributes="member: 3226">This is not necessarily true. Single genes can have incredibly significant effects even in complex phenotypes but they may only occur as relatively rare alleles in a population which may make it more difficult to find. A good example would be depression or cancer both of which are complex diseases that involve both genetics and environment where single genes can really have a strong control on the development of the illness (which is not to be miscontrued in any way as to say homosexuality is an illness, these are just examples).Weight is another example though off the top of my head I can not think of any gene outside of the leptins and the leptin receptors that have a significant effect on weight.For homosexuality in humans we have never found a reliable candiate gene that is associated with homosexuality, which does not mean there is not one, just that there are not enough people who might have the gene that it would show in any genetic profiling (SNPs, chromosomal linkage maps etc.). In drosophilia though there have been some gene knockouts that are associated with male-to-male sexual behavior.</blockquote>