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Message: <blockquote data-quote="Elder-Basilisk" data-source="post: 1673020" data-attributes="member: 3146">That rather depends upon the situation. If my character is hunting wyverns, I'm going to cast it in the morning, possibly use a rod of extension to make it last 12-18 hours and quit hunting when the duration wears out. If I have reason to suspect that we may face poison during the day (from a divination or something similar), I will take similar precautions.For mid-level battle clerics, Delay Poison 24/7 is a very good use of a 2nd level spell slot or two and a lesser metamagic rod of extend spell. Keep it up all day--it's not as if you were going to use those second level slots in combat anyway so having it help you once per six to eight fights is still a worthwhile investment.Once you get access to Hero's Feast, it's less of an issue but can keep you immune to poison during the 12 hours that Hero's Feast isn't active.</blockquote>