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Message: <blockquote data-quote="eamon" data-source="post: 3733317" data-attributes="member: 51942">The difference between fast healing and regeneration being, that if you deal 100 damage to a creature with fast healing and some ability to survive negative hitpoints, then, the moment that ability is suppressed, the creature dies as normal (with the normal yadda yadda about -1 to -9 and so on).  A regenerating creature further converts all damage to non-lethal damage (except those tryeps - like acid here - that "penetrate" the regeneration).  So to kill a 100hp troll, for instance, even after you've dealt him more than 200 damage, you're still going to need to deal 101 acid damage as a minimum.  You can try a coup de grace sometimes, but fundamentally, you're going to need a lot more effort to kill the beast.That means that an acid flask won't be enough to kill an unconscious regenerating creature, not all the time, and if the creature has a few hitpoints, then you have a problem.Further, regenerating creatures can be killed by things like suffocation.  I'm not sure if that's the flavor you're looking for, but it's something to keep in mind.So a Fast Healing creature is easier to deal with because it won't rise again very quickly (with a regenerating creature it's usually just a matter of rounds) even with a special ability to avoid normal death, and secondly, once a creature has been dropped, it's not necessary to somehow do all that lethal damage.</blockquote>