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Message: <blockquote data-quote="S'mon" data-source="post: 6898684" data-attributes="member: 463">I had this problem running my first AP (Curse of the Crimson Throne). I'm also running Runelords in 5e right now (Book 2 Skinsaw Murders, Skinsaw Man nearly TPK'd them) <img src="https://cdn.jsdelivr.net/joypixels/assets/8.0/png/unicode/64/1f600.png" class="smilie smilie--emoji" loading="lazy" width="64" height="64" alt=":D" title="Big grin    :D"  data-smilie="8"data-shortname=":D" />My advice is NOT to worry about sticking to the rails or hitting the major plot points. Treat it more like a buffet of ideas. In reality the chapters & books tend to be only loosely connected and it's natural that the PCs will miss chunks - IME this does no harm really. Just move ahead to the next natural entry point and maybe add your own material where appropriate. Eg if the PCs don't trace the Skinsaw Cult to its lair, the murders continue, maybe someone they know is attacked. If the cult is not dealt with, no problem - the PCs can still be hired for the Book 3 Fort Rannick mission. In my game Nualia TPK'd the original party and burnt Sandpoint; campaign still runs fine with minimal tweaking.</blockquote>