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Message: <blockquote data-quote="Eosin the Red" data-source="post: 423722" data-attributes="member: 168">mmaddsen -This is tricky all of a sudden - and hard to explain. There is also a bit of a professional bind here - you quoted my boss (kinda, we are decentralized but share the same governing body).40-60 mg is the correct estimation for nicotine.0.3 g has been used for nicotine sulfate as an estimated lethal level. NS is considered far more toxic than nicotine. I have never before seen 0.3 g of nicotine used as a toxic level - so I made the leap to nicotine sulfate, the EPA designated "supertoxic" cousin of Nicotine. That was a bit of an error on my part, after closely reading the referred website, they do indeed mean nicotine. They give a grossly wrong toxic level but nicotine is what they intended.Nicotine is considered highly toxic by Poison Control but it is not a red flag item  - meaning that it is evaluated on a case by case basis, as opposed to methanol which is an automatic ED referral.So now comes the confusing part - NS, dimethylmercury, & parathion are all rated supertoxic but estimated lethality is greater than 1 g, not much greater but greater. Here my lack of an rPh or chamistry degree shows - I do not really know why nictotine is only highly toxic (EPA level 3) vs NS, DMM, & Parathions supertoxic (EPA level 6). I think it has to do with available forms and ease of exposure.  Nicotine as it is found in plants & products requires a significant ingestion 1 cig might kill an infant and 5 cigs have killed a toddler (found on autopsy), I have yet to see any data on how many cigs it would take to do in a 70 kg man. NS can kill with an estimated 6-7 drops on skin!The data previously quoted does come from an interesting website but quoting a non-govermental web site is still poor form in science/health discussions. I looked closely at the site to see if I could see what was going on. [Note: I missed that the site is referenced up top first time through]. I have no idea where they get the 0.3 g maybe in '93 that was how it was expressed? but 300 mg should kill you, me, SHARK, DocM, Morrus, and PC (although, as mentioned survival has been reported after a 4 g exposure). 0.3 g is still wrong. The confusing part:40-60 mg of nicotine = estimated lethal level0.3g (actually 350 mg) of NS = estimate lethal levelNS = more toxic. Confusing huh? Maybe a chemist can explain it better?In the same vein of IANAL, since both my employer and my profession are brought up in this topic - this is not medical advice and on these boards, I do not represent my employer. Strickly IMO ~ just with references.Further replies will need to be addressed to my e-mail - <a href="mailto:eosin_the_red@cox.net">eosin_the_red@cox.net</a>.  For me, suddenly and by wild chance this conversation has turned professional <img src="https://cdn.jsdelivr.net/joypixels/assets/8.0/png/unicode/64/1f61b.png" class="smilie smilie--emoji" loading="lazy" width="64" height="64" alt=":p" title="Stick out tongue    :p"  data-smilie="7"data-shortname=":p" /> , instead of being one of my pet peeves (WAGs presented as fact). But I am happy to address any other questions or problems you have with my assessment, just not where I have to agonize over the legal/ethical implications of what I am posting.</blockquote>

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