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Message: <blockquote data-quote="Bushviper" data-source="post: 9484350" data-attributes="member: 7047663">I haven't read this thread, but I always found poisons, diseases, curses, etc. an avenue of DM'ing that is basically nullified by some extremely common player tools so I changed the entire system.At my table, all the aforementioned afflictions have a DC that must be beaten for it to be removed. There's no standard way to set the DC, but there are numerous methods that make 'sense.'Anyway, an example of my system.For example - The group fighter has been poisoned and the Cleric wants to remove it Protection of Poison. The Cleric is level 5 with a Wisdom of 16 and the poison has a DC of 13. So, the Cleric would need to roll a 7 or more to remove the poison.Pre-made items such as a potion of cure poison either has a cap of DC it can cure (i.e. up to DC 15) or has a bonus to the d20 roll (i.e. +5).Some afflictions are so powerful that they require multiple (successful) casts and/or a specific reagent to be used in conjunction with the magic. Some might even require a specific location or environmental factor. One of my players contracted lycanthropy and the only way to remove it was to cast Remove Curse (DC 16) under a full moon using wolfsbane as a material component. This doesn't solve all the problems, but it does make these things a lot more interesting for both DM and player.</blockquote>