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Message: <blockquote data-quote="Barolo" data-source="post: 7104890" data-attributes="member: 61932">I would say it should not be a problem in general, if you are able to access your enemies weaknesses and play accordingly. Surely a lot of monsters/NPCs have good con saves, and poison resistance is really common, which would usually imply that the use of poison spray usually requires a little bit more consideration. At higher levels it may start to hurt more to be dependable on save options, as monsters with spell resistance start to show up, and proficiency in saves for monsters become more commonplace.All that said, it is wise for a spellcaster to have some save spell as backup even for a more traditional attack-reliant build, if you can afford it, as there are monsters with outstanding AC for their challenge (such as hobgoblins), and you will always eventually find some odd opposition who happens to have as their Achilles heel a con save, even latter on in the game.Edit: I failed to mention you actually should not be gearing yourself to cantrip-intensive tactics in expense of your other spells in general as a spellcaster. They are, after all, your backup option. The only cantrip truly reliable for intensive use is eldritch blast, for some unique features it has (such as force type damage) and some investments that can be done towards this specific goal, which are only available for this cantrip (or, in the case of hex, best benefited through it).</blockquote>