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Message: <blockquote data-quote="Kurotowa" data-source="post: 3319769" data-attributes="member: 27957">Indeed, it's easier to say when it doesn't apply then try to list all the things it does remove.Using Iron Heart Surge requires a deliberate standard action.  So dazed, stunned, and nauseated are out, because they don't allow a standard action to be taken.  To initiate a maneuver you have to be able to move (p38), which means paralysis also prevents its use.  Charm and Dominate are out because they remove the volition required.  And since IHS only removes a single selected effect you can't use IHS and free yourself "accidentally."  Fear effects are trickier with how much volition remains.  I'd rule that panicked doesn't allow other actions, frightened and forced to fight would be acceptable, and shaken is just fine.  I'd also consider ability damage/drain to not fall under the "spell, effect, or condition" heading.That's everything that springs to mind, the rest is fair game.  Poison and disease (though it won't undo damage already done), penalties of every sort, troublesome curses and enchantments.  Just watch out for multiple effects, and consider keeping Moment of Perfect Mind ready against mind control.</blockquote>