Strangest game ever?
Well I had the party Spelljamming, and attacked them with genetically modified, swash-buckling, space-monkeys. There were also radioactive green ones, which gradually inflated and exploded on impact of the ship. They all had metal control helmets on their heads, and were created and controlled by the evil space gnome pirate coalition. The space monkey leader was an old, elder monkey with a long thin waist length moustache and cowboy boots. He rode a giant space hamster which had two canons strapped to either side of it.
Later on in the adventure the party were captured by the gnomes, and had space monkey ebriose implanted into their bodies to breed even more of the little savage bastards.
Their plan for universe domination - unfortunately - never saw fruition, as it was about this time the ship crashed head on into a planet which had accidentally gotten in the way.
I guess that adventure may qualify as pretty strange.