This is about Blue Rose, in'it?
To answer the question: it would really depend on the agenda. Someone running a "all religion is evil" game or a game of RaHoWa (a racist game) would put me off.
Edit: For that matter, even if it is an agenda of which I approve, when it is presented in a "bonk you over the head" fashion, and/or the agenda is illustrated in an exagarated characture of reality ("One wizard discarded a staff and animals started dying over the WORLD and a massive greenhouse effect started!"), it makes me wrinkle my nose a bit.