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Longer answer: No, but make sure that the effects you are considering are both marks. Things like Hunter's Quarry and Warlock's Curse are not marks. A Paladin's Divine Challenge includes a mark in it's description, so it is a mark (similar to a swordmage's aegis).
This is one problem with having 2 good defenders. They need to work together and plan ahead on who should be marking who. And, figure out ways to get their marks triggered.