This topic reminds me of (the original 80's) He-Man cartoon.
You had the world, but as part of that, Castle Greyskull (which was a prominent feature location in itself) had portals within it that led to many other worlds.
The adventures of the series mainly focused on "the He-man" world. But it did allow for single-episode side trek adventures off world. But, bottom line, they needed the main setting to be the focus to allow the baseline flavor... that way when they went to the other worlds and saw "wierd things" there was a sense of wierdness each time it happened, rather than just "oh, this new thing...again..."
But, yes, it can work. Just a matter of what your group is looking for.
You had the world, but as part of that, Castle Greyskull (which was a prominent feature location in itself) had portals within it that led to many other worlds.
The adventures of the series mainly focused on "the He-man" world. But it did allow for single-episode side trek adventures off world. But, bottom line, they needed the main setting to be the focus to allow the baseline flavor... that way when they went to the other worlds and saw "wierd things" there was a sense of wierdness each time it happened, rather than just "oh, this new thing...again..."
But, yes, it can work. Just a matter of what your group is looking for.