I've never played a gnome NPC. I don't have much interest in playing one in the future, unless something is done to wow me and get me excited.
I don't have anything actively against gnomes, they're just quite uninteresting to me, and it takes something special to get me to play a small race, as I like my movement options. Thus, as a DM, my worlds will have gnomes, and that means occasionally I'll end up playing one as an NPC -- but I didn't check the "I want to use a gnome as an NPC" because, well, it's no special desire.
In addition, the only gnome PC that I recall ever having been played in a group I was involved in was/is one of my favorite PC allies ever, but it should be noted that it's purely because he's the comic relief and awesome at it. Mad, delusional, flambouyant aspiring pirate captain gnomes definitely get my thumbs up. But then, the only reason he's a gnome is because it tends to make the character more ridiculous, and being the go-to race for taking a character less seriously isn't really a selling point to most people, nor should it be.