1. When role-play becomes amateur dramatics. Not my PF group, thankfully, but when I see and hear other D&D5 groups at our FLGS going full Shakespearian all session, it just makes me roll my eyes. Too much of that in games just leaves me cold. I'd rather get on with the game and story. This also covers when shopping turns into a full blown session because either some players or the GM want to get their role-play quota.
2. Mapping. Thankfully this hasn't been an issue for years but sometimes you get a GM that wants the party to map the dungeon themselves. Yawn. Just draw anything relevant on a battle map and let's get going.
3. Encumbrance and resource tracking. Why is this even a thing? Can we not just say you can carry anything within reason. Same thing applies with treasure. I've lost count of the number of games where the party slay the evil dragon and are faced with explaining how they cart 10,000 gold pieces and all the silver out of the dungeon. Aargh!!!
4. Dead and Waiting. I get it, there are only so many defeated adventurers you can find chained up in the same dungeon, but waiting around after your character has died to get back into the game is tedious. I've been on both sides of the fence here, and I know sometimes it cannot be helped, but it's a waste of good gaming time. Usually when this happens in a game I am running, I ask the waiting player to help me run encounters, be the monsters or track the initiatives for me, and at least that is something.
I know that #1 makes me sound like a right grump but I've enjoyed that level of role-playing. For me, role-playing is about the adventure, the story, and the game, not all the in character conversations. Sorry.