Jeff Carlsen
Adventurer
With regards to Game Science dice:
1) Take your average run of the mill Chessex or Crystal Caste or Q Workshop dice. Do some sample rolling. Let me know how many thousands and thousands of rolls you need to make before the statistical difference between them and Game Science dice manifests. I'll wait. In the meantime, I'll keep using my Chessex, Crystal Caste and Q Workshop dice.
2) Actually, using "casino design" dice and casino dice science doesn't necessarily work well for gaming anyway. Game Science dice are notorious for stopping after very few rolls, which isn't good for their vaunted randomness. In order to get a roll that's truly random, you need to have a casino-style table and you need to throw the dice all the way across it to bounce off the back edge, again, casino style, so that the dice roll sufficiently. If you're not doing this, all the pretentious "science" of Game Science dice is a moot point anyway.
You're somewhat mistaken on your second point. The more a die bounces and rolls, the greater the effect of any imperfections in weight, and thus the less equally random the die becomes.
But your first point is valid. The imperfections in most dice aren't enough to really matter at the table. Even so, it's okay to desire something better for its own sake. For some, that's more precise dice. For others, it's dice made from precious materials.