I was recently reading ohn D. Rateliff's "Brief History of Tolkien's RPGs" (
Part 1,
Part 2 and
Part 3. Within I saw this tidbit about MERP (and later, about a potential WotC Tolkien RPG):
Reading this, it occurred to me that 4E manages to handle healing without having clerics reasonably well. Given D&D's long ties to Tolkien*, I believe that 4E would be a strong base to build a D&D/Tolkien.
Yes, I do think 4E would need a major rework to fit. I would definitely simply it to be able to attract a raw beginner audience, and I would adjust other things for flavor. Still, you don't have to worry too much about cleric/animists in the RPG.